Chapter 6
Drugs Acting on Autonomic Nervous System: Adrenergic Agonists and Antagonists Agents
![Adrenergic Neurons: Neurotransmission](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14464.jpg)
Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or…
![Adrenergic Receptors (Adrenoceptors): Classification](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14465.jpg)
Adrenergic receptors, or adrenoceptors, respond to the autonomic neurotransmitter noradrenaline and other endogenous catecholamine agonists. They are…
![Adrenergic Receptors: β Subtype](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14467.jpg)
β-adrenoceptors have varied sensitivities towards adrenaline, noradrenaline, and isoprenaline. The order of agonist potency is as…
![Adrenergic Agonists: Direct-Acting Agents](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14468.jpg)
Drugs that mimic the action of endogenous catecholamines like noradrenaline and adrenaline are called adrenergic agonists or sympathomimetics. Based…
![Adrenergic Agonists: Mixed-Action Agents](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14470.jpg)
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate…
![Adrenergic Agonists: Chemistry and Structure-Activity Relationship](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14471.jpg)
Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine…
![Adrenergic Agonists: Therapeutic Uses](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14473.jpg)
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU)…
![Adrenergic Antagonists: Chemistry and Classification of ɑ-Receptor Blockers](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14474.jpg)
Adrenergic antagonists, or sympatholytics, inhibit adrenoceptor activation driven by catecholamines or agonists. Based on their adrenoceptor…
![Adrenergic Antagonists: Chemistry and Classification of β-Receptor Blockers](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14476.jpg)
β-adrenergic antagonists, or β-blockers, modulate the sympathetic nervous system by targeting β-adrenoceptors and inhibiting…
![Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14477.jpg)
β-receptor blockers significantly impact the cardiovascular system by counteracting catecholamine-induced sympathetic responses. These…
![Drugs Affecting Neurotransmitter Synthesis](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/15010.jpg)
Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example,…
![Drugs Affecting Neurotransmitter Release or Uptake](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/14479.jpg)
Certain drugs can affect how neurotransmitters called catecholamines, are released or taken back up in the adrenergic neuron. They can have different…
![Measurement of Smooth Muscle Function in the Isolated Tissue Bath-applications to Pharmacology Research](https://jovecdn2.ccindex.cn/files/thumbs/52324_t.png)
Measurement of Smooth Muscle Function in the Isolated Tissue Bath-applications to Pharmacology Research
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Isolated tissue bath assays are a classical pharmacological tool for evaluating concentration-response relationships in a myriad of contractile…
![Cardiac Response to β-Adrenergic Stimulation Determined by Pressure-Volume Loop Analysis](https://jovecdn2.ccindex.cn/files/thumbs/62057_t.png)
Determination of the cardiac function is a robust endpoint analysis in animal models of cardiovascular diseases in order to characterize effects of…