JOVE JOURNAL

Medicine

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Journal (Medicine)

Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization

Yogin Patel¹, Ji S. Lee², Hexin Chen¹

¹Department of Biological Science, Center for Colon Cancer Research,University of South Carolina, ²Department of Pathology,Chonnam National University Medical School

Journal (Medicine)

TRUE Gene Silencing: Screening of a Heptamer-type Small Guide RNA Library for Potential Cancer Therapeutic Agents

Arisa Haino*¹, Tatsuya Ishikawa*¹, Mineaki Seki¹, Masayuki Nashimoto¹

¹Research Institute for Healthy Living,Niigata University of Pharmacy and Applied Life Sciences

Journal (Medicine)

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

Hanlim Song¹, Ji-Young Park¹, Hyung-Sun Kim¹, Min-Cheol Lee², Young Kim², Hyoung-Ihl Kim^1,3

¹Department of Biomedical Science and Engineering,Gwangju Institute of Science and Technology, ²Department of Pathology,Chonnam National University Medical School, ³Departement of Neurosurgery,Presbyterian Medical Center

Journal (Medicine)

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

¹Anesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine,Massachusetts General Hospital, ²Cardiovascular Research Center and Cardiology Division of the Department of Medicine,Massachusetts General Hospital, ³Cardiovascular Division,Brigham and Women's Hospital, ⁴Harvard Medical School, ⁵Department of Anesthesiology,Uniklinik RWTH Aachen, RWTH Aachen University, ⁶Center for Immunology and Inflammatory Diseases and the Division of Rheumatology, Allergy, and Immunology of the Department of Medicine,Massachusetts General Hospital

Journal (Medicine)

Exosomal miRNA Analysis in Non-small Cell Lung Cancer (NSCLC) Patients’ Plasma Through qPCR: A Feasible Liquid Biopsy Tool

Marco Giallombardo*^1,2, Jorge Chacártegui Borrás*^2,3, Marta Castiglia⁴, Nele Van Der Steen³, Inge Mertens^5,6, Patrick Pauwels^7,3, Marc Peeters^8,3, Christian Rolfo^2,3

¹Department of Biopathology and Medical Biotechnology, Section of Biology and Genetics,University of Palermo, ²Phase I-Early Clinical Trials Unit, Oncology Department,Antwerp University Hospital (UZA), ³Center for Oncological Research (CORE),Antwerp University, ⁴Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology,University of Palermo, ⁵Flemish Institute for Technological Research (VITO), ⁶CORE, Campus Groenenborger,Antwerp University, ⁷Molecular Pathology, Pathology Department,Antwerp University Hospital (UZA), ⁸Oncology Department,Antwerp University Hospital (UZA)

Journal (Medicine)

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Lee Chin^1,2, Elina Korpela³, Anthony Kim¹, Darren Yohan², Carolyn Niu⁴, Brian C. Wilson³, Stanley K. Liu^1,3

¹Department of Radiation Oncology,University of Toronto, ²Department of Physics,Ryerson University, ³Department of Medical Biophysics,University of Toronto, ⁴Ontario Cancer Institute / Campbell Family Institute for Cancer Research

Journal (Medicine)

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

Jessica N. Blom¹, Xiangru Lu¹, Paul Arnold¹, Qingping Feng¹

¹Department of Physiology and Pharmacology,Western University

Journal (Medicine)

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

Joshua J. Timmons¹, Sean Cohessy², Eric T. Wong¹

¹Brain Tumor Center & Neuro-Oncology Unit, Department of Neurology,Beth Israel Deaconess Medical Center & Harvard Medical School, ²Division of Cancer Genetics, Department of Medicine,Beth Israel Deaconess Medical Center & Harvard Medical School

Journal (Medicine)

Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Bailey Miskew Nichols*¹, Yoshitsugu Aoki*², Mutsuki Kuraoka², Joshua J.A. Lee¹, Shin'ichi Takeda², Toshifumi Yokota¹

¹Department of Medical Genetics,University of Alberta Faculty of Medicine and Dentistry, ²Department of Molecular Therapy, National Institute of Neuroscience,National Center of Neurology and Psychiatry

Journal (Medicine)

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Ahmed E. Hegab¹, Naofumi Kameyama¹, Aoi Kuroda¹, Shizuko Kagawa¹, Yongjun Yin², David Ornitz², Tomoko Betsuyaku¹

¹Division of Pulmonary Medicine,Keio University School of Medicine, ²Department of Developmental Biology,Washington University School of Medicine

Journal (Medicine)

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Xiuhua A. Si¹, Jinxiang Xi²

¹Department of Mechanical Engineering,California Baptist University, ²School of Engineering and Technology,Central Michigan University

Journal (Medicine)

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Mark Nowell¹, Roman Rodionov¹, Gergely Zombori², Rachel Sparks², Michele Rizzi¹, Sebastien Ourselin², Anna Miserocchi³, Andrew McEvoy³, John Duncan¹

¹Department of Clinical and Experimental Epilepsy,UCL Institute of Neurology, ²Center of Medical Imaging and Computing,UCL, ³Department of Neurosurgery,National Hospital for Neurology and Neurosurgery

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