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Deep Brain Stimulation for Treatment of Major Depression

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Closed-Loop-Neurostimulation zur Biomarker-gesteuerten, personalisierten Behandlung schwerer depressiver Störungen

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

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Closed-Loop-Neurostimulation zur Biomarker-gesteuerten, personalisierten Behandlung schwerer depressiver Störungen

Deep Brain Stimulation for Treatment of Major Depression

DOI:

10.3791/65177-v

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01:13 min

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July 07, 2023

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Kristin K. Sellers², Ankit N. Khambhati², Noah Stapper³, Joline M. Fan⁴, Vikram R. Rao⁴, Katherine W. Scangos³, Edward F. Chang², Andrew D. Krystal³

¹Department of Neurological Surgery,University of California, San Francisco, ²Weill Institute for Neurosciences,University of California, San Francisco, ³Department of Psychiatry and Behavioral Sciences,University of California, San Francisco, ⁴Department of Neurology,University of California, San Francisco

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Keywords: Closed-loop Neurostimulation Major Depressive Disorder Biomarker Personalized Treatment Deep Brain Stimulation Neural Biomarker Symptom Severity Continuous Stimulation Closed-loop Stimulation Treatment-refractory MDD State-space Model Neural Features

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