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Modeling an Enzyme Active Site using Molecular Visualization Freeware
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Bioquímica
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JoVE Journal Bioquímica
Modeling an Enzyme Active Site using Molecular Visualization Freeware

Modeling an Enzyme Active Site using Molecular Visualization Freeware

DOI:
10.3791/63170-v

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14:37 min

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December 25, 2021

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, , , , ,
1The University of Texas at Austin, 2Mount Mary University, 3College of St. Benedict/St. John’s University, 4Wabash College

Capítulos

  • 00:05Introduction
  • 01:42Protocol: UCSF ChimeraX
  • 03:14Results: UCSF ChimeraX
  • 03:33iCN3D Protocol
  • 06:38Results: iCN3D
  • 07:02Protocol: Jmol
  • 09:47Results: Jmol
  • 10:08Protocol: PyMOL
  • 12:56Results: PyMOL
  • 14:01Conclusion

Summary

Tadução automática

Tadução automática

A key skill in biomolecular modeling is displaying and annotating active sites in proteins. This technique is demonstrated using four popular free programs for macromolecular visualization: iCn3D, Jmol, PyMOL, and UCSF ChimeraX.

Tags

Keywords: Molecular VisualizationEnzyme Active SiteGlucokinasePDBID 3FGULigandsSubstrate AnalogCatalytic ComplexBinding InteractionsUCSF ChimeraXMolecular ModelingBiological MacromoleculesVisualization Software

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