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Direct Drug Delivery to Kidney via the Renal Artery
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Medicina
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JoVE Journal Medicina
Direct Drug Delivery to Kidney via the Renal Artery

Direct Drug Delivery to Kidney via the Renal Artery

DOI:
10.3791/61932-v

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11:18 min

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April 17, 2021

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, , , , , , , ,
1Bioscience Renal, Research and Early Development, Cardiovascular, Renal and Metabolism,BioPharmaceuticals R&D, 2Cell/mol Pharmacology, Research and Early Development, Cardiovascular, Renal and Metabolism,BioPharmaceuticals R&D, 3CVRM Safety,Safety, Clinical Pharmacology & Safety Sciences, R&D, 4Department of Cardiovascular and Renal Research,University of Southern Denmark, 5Clinical Renal, Late-stage Development, Cardiovascular, Renal and Metabolism,BioPharmaceuticals R&D

Capítulos

  • 00:00Introduction
  • 00:25Protocol
  • 10:41Representative Results
  • 10:54Conclusion

Summary

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This manuscript describes a method for targeted delivery to a single kidney via a catheter placed in the infrarenal abdominal aorta in the mouse.

Tags

Keywords: Direct Drug DeliveryRenal ArteryKidneyRenal ResearchDirected InjectionsRenal ExposureAortaAbdominal CavitySurgeryRetractorsLigatureAorta DissectionSalineNervesParalyzes

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