By running the Pathway Association Study Tool (PAST), either through the Shiny application or through the R console, researchers can gain a deeper understanding of the biological meaning of their genome-wide association study (GWAS) results by investigating the metabolic pathways involved.
Thrash, A., Warburton, M. L. A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information. J. Vis. Exp. (161), e61268, doi:10.3791/61268 (2020).