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1Sheikh Zayed Institute for Pediatric Surgical Innovation,Children’s National Hospital, 2Children’s National Heart Institute,Children’s National Hospital, 3Center for Neuroscience Research,Children’s National Hospital, 4Department of Biomedical Engineering, School of Engineering,University of Alabama at Birmingham, 5Department of Pediatrics, Department of Pharmacology & Physiology, School of Medicine and Health Sciences,George Washington University
Capítulos
- 00:05Título
- 01:02Heart Excision and Langendorff Perfusion
- 02:42Electrophysiology Study
- 05:17Transmembrane Voltage and Intracellular Calcium Optical Mapping
- 06:55Cleanup
- 07:20Results: Representative Optical Data from Langendorff-Perfused Model Hearts
- 08:59Conclusion
O objetivo deste estudo foi estabelecer um método de investigação da dinâmica cardíaca por meio de um modelo animal translacional. A abordagem experimental descrita incorpora optocardiografia de dupla emissão em conjunto com um estudo eletrofisiológico para avaliar a atividade elétrica em um modelo cardíaco suíno isolado e intacto.
