We introduce a semi-automatic protocol for shape analysis on brain structures, including image segmentation using open software, and further group-wise shape analysis using an automated modeling package. Here, we demonstrate each step of the 3D shape analysis protocol with hippocampal segmentation from brain MR images.
Kim, J., Valdés Hernández, M. d. C., Park, J. Three-Dimensional Shape Modeling and Analysis of Brain Structures. J. Vis. Exp. (153), e59172, doi:10.3791/59172 (2019).