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大鼠部分视神经切断术: 建立一种新的手术方法评价视网膜神经节细胞二次变性的模型

JoVE Journal
Neurociência
Author Produced

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JoVE Journal Neurociência

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

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大鼠部分视神经切断术: 建立一种新的手术方法评价视网膜神经节细胞二次变性的模型

DOI:

10.3791/56272-v

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13:12 min

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October 15, 2017

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Fancheng Yan, Sailiang Guo, Yijie Chai, Lan Zhang, Kegao Liu, Qingjun Lu, Ningli Wang, Shuning Li

¹Aier School of Ophthalmology,Central South University, Changsha, China, ²Institute of Immunology,Tsinghua University School of Medicine, Beijing, China, ³Beijing Tongren Eye Center,Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China, ⁴Beijing Institute of Ophthalmology,Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China

Capítulos

00:00Título
03:08Surgical Approach
06:17Assessing the Optic Nerve
08:50Closing and Recovery
09:54Representative Results
11:53Conclusion

Summary

Tadução automática

视网膜神经节细胞 (视网膜) 继发性变性通常发生于青光眼。本研究介绍了一种创新的手术方式部分视神经横断。利用这种节省空间的操作方法扩展了模型的应用范围, 并允许在视网膜中探索二次损伤机制的新方法。

Tags

Keywords: Partial Optic Nerve Transection Secondary Degeneration Retinal Ganglion Cells Glaucoma Novel Surgical Approach Space-saving Technique Optic Nerve Stabilization Primary And Secondary Injury

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