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1Department of Anesthesiology,Ohio State University College of Medicine, 2Department of Anesthesiology and Pain Medicine,Nationwide Children’s Hospital, 3Department of Anaesthesia and Critical Care Medicine,University of Toronto, 4Department of Biomedical Sciences, Section of Anatomic Pathology,Cornell University College of Veterinary Medicine, 5Department of Pathology and Anatomy,Ohio State University College of Medicine, 6Department of Pathology and Laboratory Medicine,Nationwide Children’s Hospital
Capítulos
- 00:05Título
- 00:45Preparing the Animal
- 02:49Femoral Artery Catheterization
- 04:11Collecting Data and Completing Surgery
- 05:30Results: Consistency and Reproducibility of Lab Values
- 06:07Conclusion
Anestesi-induceret udviklingstoksicitet (AIDN) -forskning har fokuseret på gnavere, som ikke er bredt anvendelige for mennesker. Ikke-menneskelige primatmodeller er mere relevante, men er cost-prohibitive og vanskelige at bruge til forsøg. Grisetten er derimod en klinisk relevant, praktisk dyremodel, der er ideel til undersøgelse af anæstetisk neurotoksicitet.
Tags
Keywords:
Piglet ModelAnesthetic-induced Developmental Neurotoxicity (AIDN)Translational NeurosciencePhysiologic HomeostasisAnesthesia InductionPulse OximetryBlood PressureElectrocardiographyTemperatureTracheal IntubationLidocaineEnd-tidal Carbon DioxideOphthalmic OintmentAntibioticSterile FieldFemoral Neurovascular Bundle
