Here we describe a protocol using the web-based drug repurposing hypothesis generation tool: "RE:fine Drugs." This protocol can be modified to a user's preferences at the level of the query type (gene, drug or disease) and/or the range of available advanced options.
Regan, K., Moosavinasab, S., Payne, P., Lin, S. Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System. J. Vis. Exp. (118), e54948, doi:10.3791/54948 (2016).