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Utilizzando Genomica Funzionale screening per identificare gli obiettivi farmaco potenzialmente romanzo in Cancer Cell Culture Spheroid
JoVE Journal
Pesquisa do Câncer
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JoVE Journal Pesquisa do Câncer
Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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Utilizzando Genomica Funzionale screening per identificare gli obiettivi farmaco potenzialmente romanzo in Cancer Cell Culture Spheroid

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07:48 min

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December 26, 2016

DOI:

10.3791/54738-v

DOI:
10.3791/54738-v

•

07:48 min
December 26, 2016

•

4 Views
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1The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer,The Institute of Cancer Research, 2Division of Molecular Pathology,The Institute of Cancer Research, 3Institute of Cancer Sciences,University of Manchester

Tags

Functional GenomicsSiRNA ScreenCancer Cell Spheroid3D CultureHypoxiaTargeted ScreenOncogenesTumor SuppressorsCell ViabilityApoptosisTransfectionCell CultureCell CountingHigh-throughput Screening

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Morrison, E., Wai, P., Leonidou, A., Bland, P., Khalique, S., Farnie, G., Daley, F., Peck, B., Natrajan, R. Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures. J. Vis. Exp. (118), e54738, doi:10.3791/54738 (2016).

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