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기능 유전체학에게 검사를 활용하여 암 세포 회전 타원체 문화에 잠재적으로 소설 약 표적을 식별하는
JoVE Journal
Pesquisa do Câncer
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JoVE Journal Pesquisa do Câncer
Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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기능 유전체학에게 검사를 활용하여 암 세포 회전 타원체 문화에 잠재적으로 소설 약 표적을 식별하는

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07:48 min

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December 26, 2016

DOI:

10.3791/54738-v

DOI:
10.3791/54738-v

•

07:48 min
December 26, 2016

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1The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer,The Institute of Cancer Research, 2Division of Molecular Pathology,The Institute of Cancer Research, 3Institute of Cancer Sciences,University of Manchester

Tags

Functional GenomicsSiRNA ScreenCancer Cell Spheroid3D CultureHypoxiaTargeted ScreenOncogenesTumor SuppressorsCell ViabilityApoptosisTransfectionCell CultureCell CountingHigh-throughput Screening

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Morrison, E., Wai, P., Leonidou, A., Bland, P., Khalique, S., Farnie, G., Daley, F., Peck, B., Natrajan, R. Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures. J. Vis. Exp. (118), e54738, doi:10.3791/54738 (2016).

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