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الاستفادة من علم الجينوم وظيفية الفرز لتحديد أهداف المخدرات رواية يحتمل في الثقافات كروي الخلية السرطانية

JoVE Journal
Pesquisa do Câncer

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JoVE Journal Pesquisa do Câncer

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

Please note that all translations are automatically generated. Click here for the English version.

الاستفادة من علم الجينوم وظيفية الفرز لتحديد أهداف المخدرات رواية يحتمل في الثقافات كروي الخلية السرطانية

10,899 Views

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07:48 min

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December 26, 2016

DOI:

10.3791/54738-v

DOI:

10.3791/54738-v

•

07:48 min

December 26, 2016

•

4 Views

Eamonn Morrison², Patty Wai², Andri Leonidou², Philip Bland², Saira Khalique², Gillian Farnie, Frances Daley, Barrie Peck², Rachael Natrajan²

¹The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer,The Institute of Cancer Research, ²Division of Molecular Pathology,The Institute of Cancer Research, ³Institute of Cancer Sciences,University of Manchester

Tags

Functional Genomics SiRNA Screen Cancer Cell Spheroid 3D Culture Hypoxia Targeted Screen Oncogenes Tumor Suppressors Cell Viability Apoptosis Transfection Cell Culture Cell Counting High-throughput Screening

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