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November 01, 2016
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Nucleic acids are common analytes for assessing biological systems; however, bias from enzymatic manipulation can cause concern. Here a method is described for label-free detection of nucleic acids using polyaniline. This sensitive, cost-effective sensor technology can distinguish single nucleotide differences between molecules.
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Sengupta, P. P., Gloria, J. N., Parker, M. K., Flynt, A. S. A Polyaniline-based Sensor of Nucleic Acids. J. Vis. Exp. (117), e54590, doi:10.3791/54590 (2016).
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