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In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments
 

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

Article DOI: 10.3791/54576-v • 10:32 min • October 25th, 2016
October 25th, 2016 •
1, 2, 3, 4, 1, 5, 3, 1, 1
1Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, 2Visceral Pain Group, Discipline of Medicine, University of Adelaide, 3Department of Biomedical Sciences, University of Sheffield, 4Department of Pharmacy, Pharmacology and Postgraduate Medicine, University of Hertfordshire, 5Department of Gastroenterology and Hepatology, Antwerp University Hospital

Capítulos

Resumo
Automatic Translation

Mesenteric afferent nerves convey information from the gastrointestinal tract towards the brain regarding normal homeostasis as well as pathophysiology. Gastrointestinal afferent nerve activity can be assessed by mounting isolated intestinal segments with attached afferent nerves into an organ bath, isolating the nerve, and assessing basal as well as stimulated activity.

Tags

In Vitro Recording Mesenteric Afferent Nerve Activity Mouse Jejunal Colonic Segments Neuroscience Disease States Nerve Discharge Recording Nerve Sensitization Irritable Bowel Syndrome Pain Syndromes Single Unit Analysis Abdominal Midline Incision Krebs Solution Jejunum Excision
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