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تحديد البروتينات ملزمة جزيء صغير في الخلوي البيئة الأصلية التي تعيش خلية Photoaffinity وصفها

JoVE Journal
Bioquímica

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JoVE Journal Bioquímica

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

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تحديد البروتينات ملزمة جزيء صغير في الخلوي البيئة الأصلية التي تعيش خلية Photoaffinity وصفها

12,323 Views

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10:49 min

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September 20, 2016

DOI:

10.3791/54529-v

DOI:

10.3791/54529-v

•

10:49 min

September 20, 2016

•

10 Views

Sarah A. Head, Jun O. Liu²

¹Department of Pharmacology and Molecular Sciences,Johns Hopkins University School of Medicine, ²Department of Oncology,Johns Hopkins University School of Medicine

Tags

Small Molecule Binding Proteins Photoaffinity Labeling Live-cell Molecular Mechanism Drug Target Protein Identification Native Cellular Environment

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