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A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
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JoVE Journal Química
A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

10,358 Views

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09:04 min

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September 09, 2016

DOI:

10.3791/53593-v

DOI:
10.3791/53593-v

•

09:04 min
September 09, 2016

•

1 Views
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1Department of Chemistry,Central Washington University, 2Department of Chemistry,Utah Valley University

Tags

GuanidinylationAminoguanidineNatural Product SynthesisClavatadine ADirect Synthetic ApproachProtecting Group Strategy24-dibromo Homogentisic Acid LactoneHunig’s BaseIsocyanateDichloromethaneCannula TransferReaction Mixture

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Malmberg, C. E., Chamberland, S. A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products. J. Vis. Exp. (115), e53593, doi:10.3791/53593 (2016).

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