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光遗传学功能磁共振成像
JoVE Journal
Neurociência
This content is Free Access.
JoVE Journal Neurociência
Optogenetic Functional MRI
DOI:

06:06 min

April 19, 2016

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Capítulos

  • 00:05Título
  • 00:51Stereotaxic Implantation Surgery and Virus Injection
  • 02:31Optogenetic Functional MRI
  • 04:20Results: Optogenetic fMRI Enables Detection of Neuronal Activity in Response to Stimulation of the Motor Cortex
  • 04:58Conclusion

Summary

Tadução automática

This protocol describes the steps and data analysis required to successfully perform optogenetic functional magnetic resonance imaging (ofMRI). ofMRI is a novel technique that combines high-field fMRI readout with optogenetic stimulation, allowing for cell type-specific mapping of functional neural circuits and their dynamics across the whole living brain.

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