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JoVE Journal Neuroscience
A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
 

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

Article DOI: 10.3791/52642-v • 10:05 min • May 7th, 2017
May 7th, 2017 •
*1, *1, 1, 1, 1
1Canadian Center for Behavioural Neuroscience, University of Lethbridge
* These authors contributed equally

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This protocol presents a method for creating a large unilateral craniotomy over the temporal and parietal regions of the mouse cerebral cortex. This is especially useful for real time imaging over an expansive area of a cortical hemisphere.

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Large Lateral Craniotomy Wide-field Optical Imaging Brain Activity Cortical Hemisphere Optogenetics Neural Dynamics Temporal And Spatial Resolutions Hemmorage Cortical Damage Dura Attachment Blood Vessels Neurobiological Mechanisms Brain Circuit Development Alzheimer's Disease Stroke Surgical Supplies Sterility Head Holder Setup Thermo-regulating Heating Pad Teeth Holder
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