This content is Free Access.
26,673 Views
•
09:05 min
•
May 04, 2015
DOI:
Summary
Automatically generated
A highly reproducible model for myocardial infarction in mice with minimal invasive manipulations is described. The model can be easily performed, resulting in a high reproducibility and survival rate. Thus, the described model will reduce the number of required animals as requested by the 3R principle (Replacement, Refinement and Reduction).
Read Article
Cite this Article
Curaj, A., Simsekyilmaz, S., Staudt, M., Liehn, E. Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice. J. Vis. Exp. (99), e52197, doi:10.3791/52197 (2015).
Copy