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完整的胸腺切除术的成年大鼠非侵入气管插管
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation
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完整的胸腺切除术的成年大鼠非侵入气管插管

16,231 Views

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08:35 min

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December 29, 2014

DOI:

10.3791/52152-v

DOI:
10.3791/52152-v

•

08:35 min
December 29, 2014

•

7 Views
, , , ,
1Department of Surgery,Duke University Medical Center, 2Department of Pediatrics,Duke University Medical Center, 3Department of Immunology,Duke University Medical Center

Summary

Automatically generated

Rodent thymectomy is a valuable technique in immunological research. Here, a protocol for complete thymectomy in adult rats using a mini-sternotomy along with non-invasive intubation and positive pressure ventilation to minimize perioperative morbidity and mortality is described.

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Cite this Article

Rendell, V. R., Giamberardino, C., Li, J., Markert, M. L., Brennan, T. V. Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation. J. Vis. Exp. (94), e52152, doi:10.3791/52152 (2014).

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