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タンパク質の削除の誘導を介して<em>子宮内で</em>エレクトロポレーションは、トランスジェニックモデルにおいて神経細胞の移動の欠損を定義する
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タンパク質の削除の誘導を介して<em>子宮内で</em>エレクトロポレーションは、トランスジェニックモデルにおいて神経細胞の移動の欠損を定義する
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January 12, 2015
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Summary
Automatically generated
Neuron migration is regulated by numerous cell autonomous and non-cell autonomous factors. This protocol shows how in utero electroporation can be used to determine whether a phenotype in a transgenic mouse is due to disruption of a cell intrinsic mechanism or impairment of interaction between the neuron and its environment.
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Svoboda, D. S., Clark, A., Park, D. S., Slack, R. S. Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models. J. Vis. Exp. (95), e51983, doi:10.3791/51983 (2015).
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