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1Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery,David Geffen School of Medicine at University of California, Los Angeles (UCLA), 2PerkinElmer, 3Department of Dermatology,Johns Hopkins University School of Medicine, 4Department of Medicine, Division of Infectious Diseases, Department of Orthopaedic Surgery,Johns Hopkins University School of Medicine
Capítulos
- 00:05Título
- 01:51Mouse Surgical Procedure
- 03:562D Optical Imaging (In vivo Bioluminescent and Fluorescent Imaging)
- 06:35µCT Image Acquisition
- 08:113D Optical Image Acquisition, Formation and µCT Co-registration
- 12:18µCT Image Analysis
- 16:09Results: Representative Bioluminescent and µCT Images
- 17:49Conclusion
Combinato imaging ottico e μCT in un modello murino di infezione impianto ortopedico, utilizzando un ceppo ingegnerizzato bioluminescente di Staphylococcus aureus, purché la capacità di monitorare in maniera non invasiva e longitudinalmente la dinamica della infezione batterica, così come la risposta infiammatoria corrispondente e cambiamenti anatomici nel osso.
