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巴恩斯迷宫测试策略与小型和大型啮齿类动物模型

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JoVE Journal Comportamento

Barnes Maze Testing Strategies with Small and Large Rodent Models

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巴恩斯迷宫测试策略与小型和大型啮齿类动物模型

DOI:

10.3791/51194-v

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12:59 min

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February 26, 2014

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Cheryl S. Rosenfeld*¹, Sherry A. Ferguson*²

¹Biomedical Sciences and Bond Life Sciences Center,University of Missouri, ²Division of Neurotoxicology, National Center for Toxicological Research,Food and Drug Administration

Capítulos

00:05Título
01:27Overview of the Barnes Maze for Small Rodents
02:58Running the Barnes Maze with Mice
05:50Setting up the Barnes maze for Rats Without Tracking
07:20Running the Barnes Maze with Rats
09:46Results: Maze Assessment of Polygamous and Monogamous Mice Fed Bisphenol A Supplemented Diets
12:23Conclusion

Summary

Tadução automática

在旱地巴恩斯迷宫被广泛用于测量响应于轻度厌恶刺激空间导航能力。连续多天，对照组的性能（如等待时间来寻找逃生笼）提高，表明正常的学习和记忆。大鼠和小鼠之间的差异必然要求，在这里详细的设备和方法的变化。

Tags

Keywords: Barnes Maze Spatial Learning Spatial Memory Rodents Mice Rats Navigation Water Maze Extra-maze Cues Intra-maze Cues Search Strategy Latency Distance Traveled Velocity Time Spent Automated Tracking

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