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末梢神経損傷後の機能回復を評価する嗅神経鞘細胞の移植

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury

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末梢神経損傷後の機能回復を評価する嗅神経鞘細胞の移植

11,652 Views

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10:33 min

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February 23, 2014

DOI:

10.3791/50590-v

DOI:

10.3791/50590-v

•

10:33 min

February 23, 2014

•

4 Views

Nicolas Guerout^1,2, Alexandre Paviot^1,3, Nicolas Bon-Mardion^1,3, Axel Honoré¹, Rais OBongo^1,4, Célia Duclos¹, Jean-Paul Marie^1,3

¹UPRES EA3830, Institute for Research and Innovation in Biomedicine,University of Rouen, ²Neurociência,Karolinska Institutet, ³Otorhinolaryngology, Head and Neck Surgery Department,Rouen University Hospital, ⁴Otorhinolaryngology, Head and Neck Surgery Department,Amiens University Hospital

Summary

嗅神経鞘細胞（たOEC）が、一次嗅覚ニューロンの成長を可能にする神経堤細胞である。この特定のプロパティは、細胞移植のために使用することができる。ここでは喉頭神経損傷モデルでたOECの使用に基づいて細胞移植のモデルを提示。

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