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세포에 붙어 Antileishmanial 검사에 대한 기생충 구조 및 변화 분석<em> Leishmania donovani</emTHP1 인간 급성 백혈병 Monocytic 셀 라인에서> Amastigotes
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
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세포에 붙어 Antileishmanial 검사에 대한 기생충 구조 및 변화 분석<em> Leishmania donovani</emTHP1 인간 급성 백혈병 Monocytic 셀 라인에서> Amastigotes

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12:22 min

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December 30, 2012

DOI:

10.3791/4054-v

DOI:
10.3791/4054-v

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12:22 min
December 30, 2012

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2 Views
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1National Center for Natural Products Research, School of Pharmacy,University of Mississippi, 2Department of Pharmacology,University of Mississippi

Tags

Parasite RescueTransformation AssayAntileishmanial ScreeningIntracellular Leishmania Donovani AmastigotesTHP1 Human Acute Monocytic Leukemia Cell LineLeishmaniasisNeglected DiseasesDeveloping CountriesRisk Of Contracting LeishmaniasisVisceral LeishmaniasisLimited Drug OptionsTherapeutic Doses ToxicityMultiple Drug ResistanceAnti-leishmanial Drug Discovery PipelineIn Vitro Screening ModelsPromastigotes AssayAxenic Amastigotes AssayMacrophage-amastigotes Model

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Jain, S. K., Sahu, R., Walker, L. A., Tekwani, B. L. A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line. J. Vis. Exp. (70), e4054, doi:10.3791/4054 (2012).

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