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A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities
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モノクローナル抗体ベースのタンパク質治療薬の質量を計算するためのモノクローナル抗体アプリケーションの実行
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Bioquímica
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JoVE Journal Bioquímica
Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics
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モノクローナル抗体ベースのタンパク質治療薬の質量を計算するためのモノクローナル抗体アプリケーションの実行

A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities

DOI:
10.3791/200341-v

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03:04 min

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June 16, 2023

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, ,
1GlaxoSmithKline, 2Merck, 3Moderna

Tags

Keyword Extraction: MAbscale ApplicationMonoclonal AntibodyProtein TherapeuticsHeavy ChainLight ChainBispecific AntibodiesTerminal CyclizationC Terminal ClippingChemical ModificationsLinkerPayloadAntibody Drug ConjugatesDisulfide BondsGlycosylationMass CalculationMass ErrorMonoclonal Antibody StandardN-linked GlycosylationBispecific Monoclonal AntibodyAntibody Drug Conjugate

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