2.6:

Accuracy and Errors in Hypothesis Testing

JoVE Core
Pharmacokinetics and Pharmacodynamics
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JoVE Core Pharmacokinetics and Pharmacodynamics
Accuracy and Errors in Hypothesis Testing

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01:13 min

October 10, 2024

Hypothesis testing is a fundamental statistical tool that begins with the assumption that the null hypothesis H0 is true. During this process, two types of errors can occur: Type I and Type II. A Type I error refers to the incorrect rejection of a true null hypothesis, while a Type II error involves the failure to reject a false null hypothesis.

In hypothesis testing, the probability of making a Type I error, denoted as α, is commonly set at 0.05. This significance level indicates a 5% chance of mistakenly rejecting a true null hypothesis. Conversely, the probability of making a Type II error, denoted as β, is typically set at 0.2 or less, representing the desired power. The power of a study, referred to as 1 – β, reflects the study's ability to detect a true effect, with a desired power level often set at 80% or higher.

The effect size, represented by Δ, quantifies the magnitude of difference between the populations being compared in a hypothesis test. It helps determine the practical significance of the difference and is a crucial factor in interpreting study results.

Study accuracy and precision are key evaluation metrics in hypothesis testing. Accuracy refers to the degree of closeness between a measured value and the true value. It reflects the correctness of the test results and indicates the absence of systematic errors.

Precision, on the other hand, reflects the reproducibility of results. It highlights the closeness of multiple measurements obtained under similar conditions. High precision signifies low variability among repeated measurements, indicating reliable and consistent results.

However, it's important to note that systematic errors can introduce bias and lead to inaccurate results. Systematic errors cause consistent deviations from the true value, which can affect the validity and reliability of a study. Minimizing or correcting such errors is essential to ensure the integrity of research findings.

Understanding hypothesis testing and these key evaluation metrics allows researchers to make informed decisions, interpret results accurately, and draw meaningful conclusions from their studies.