Gwangju Institute of Science and Technology 8 articles published in JoVE Engineering 4D Printed Bifurcated Stents with Kirigami-Inspired Structures Dahong Kim1, Taeyoung Kim1, Yong-Gu Lee1 1School of Mechanical Engineering, Gwangju Institution of Science and Technology Using a 3D printer, a shape memory polymer filament is extruded to form a branched tubular structure. The structure is patterned and shaped such that it can contract into a compact form once folded and then return to its formed shape when heated. Engineering Fabrication of Flexible Image Sensor Based on Lateral NIPIN Phototransistors Hyun Myung Kim*1, Gil Ju Lee*1, Min Seok Kim1, Young Min Song1 1School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology We present a detailed method to fabricate a deformable lateral NIPIN phototransistor array for curved image sensors. The phototransistor array with an open mesh form, which is composed of thin silicon islands and stretchable metal interconnectors, provides flexibility and stretchability. The parameter analyzer characterizes the electrical property of the fabricated phototransistor. Neuroscience Visual Evoked Potential Recordings in Mice Using a Dry Non-invasive Multi-channel Scalp EEG Sensor Chanmi Yeon1, Donghyeon Kim2, Kiseon Kim2, Euiheon Chung1,3 1Department of Biomedical Science and Engineering (BMSE), Gwangju Institute of Science and Technology (GIST), 2School of Electrical Engineering and Computer Science (EECS), Gwangju Institute of Science and Technology (GIST), 3School of Mechanical Engineering (SME), Gwangju Institute of Science and Technology (GIST) We designed a dry-type 16 channel EEG sensor which is non-invasive, deformable, and re-usable. This paper describes the whole process from manufacturing the proposed EEG electrode to signal processing of visual evoked potential (VEP) signals measured on a mouse scalp using a dry non-invasive multi-channel EEG sensor. Neuroscience Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications Joho Yun1, Jinhwan Kim2, Jong-Hyun Lee1,2 1Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), 2School of Mechanical Engineering, Gwangju Institute of Science and Technology (GIST) The fabrication method for fine interdigitated electrodes (gap and width: 20 µm) at the tip of a hypodermic needle (diameter: 720 µm) is demonstrated using a spray coating and flexible film photomask in the photolithography process. Engineering Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition Young Jin Yoo1, Gil Ju Lee1, Kyung-In Jang2, Young Min Song1 1School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, 2Department of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology We present a detailed method for fabricating ultra-thin color films with improved characteristics for optical coatings. The oblique angle deposition technique using an electron beam evaporator allows improved color tunability and purity. Fabricated films of Ge and Au on Si substrates were analyzed by reflectance measurements and color information conversion. Engineering Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment Jung-Dae Kim1, Yong-Gu Lee2 1Division of Scientific Instrumentation, Korea Basic Science Institute (KBSI), 2School of Mechanical Engineering, Gwangju Institute of Science and Technology (GIST) A microchip fabrication process that incorporates plasmonic tweezers is presented here. The microchip enables the imaging of a trapped particle to measure maximal trapping forces. Medicine Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique Hanlim Song1, Ji-Young Park1, Hyung-Sun Kim1, Min-Cheol Lee2, Young Kim2, Hyoung-Ihl Kim1,3 1Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, 2Department of Pathology, Chonnam National University Medical School, 3Departement of Neurosurgery, Presbyterian Medical Center This manuscript describes a modeling technique of capsular infarct. Here we utilized a modified photothrombotic technique with low intensity of light after pre-surgery target mapping. Using this technique, we created a circumscribed capsular infarct model with persistent motor impairment. Neuroscience Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium Sung Wook Park1,2, Jin Hyoung Kim2, Woo Jin Park3, Jeong Hun Kim1,2,4 1Department of Biomedical Sciences, Seoul National University College of Medicine, 2FARB Laboratory, Biomedical Research Institute, Seoul National University Hospital, 3College of Life Sciences, Gwangju Institute of Science and Technology, 4Department of Ophthalmology, Seoul National University College of Medicine Subretinal injection is a surgical technique for effective gene delivery to retinal pigment epithelium in the mouse eye. Here we describe an easy and replicable method for subretinal injection of viral vectors to retinal pigment epithelium in experimental mice.