The Affiliated Drum Tower Hospital of Nanjing University Medical School 1 article published in JoVE Developmental Biology Generation of a Mouse Artificial Decidualization Model with Ovariectomy for Endometrial Decidualization Research Yang Zhang*1,2,3, Zhe Zhang*1,2,3, Nannan Kang1,2,3, Xiaoqiang Sheng1,2,3 1Center for Reproductive Medicine and Obstetrics and Gynecology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 2State Key Laboratory of Reproductive Medicine, Nanjing Medical University, 3Center for Molecular Reproductive Medicine, Nanjing University Here, we describe the method of generating an artificial decidualization model using the ovariectomized mouse, a classic endometrial decidualization experiment in the research field of endometrial decidualization.