1Neuromuscular and Neurogenetic Disorders of Childhood Section, National Institute of Neurological Disorders and Stroke,National Institutes of Health, 2The Dubowitz Neuromuscular Centre, Molecular Neurosciences Section, Developmental Neurosciences Research and Teaching Department, Great Ormond Street Institute of Child Health,University College London, 3Department of Molecular Microbiology and Immunology,University of Southern California, 4NIHR Great Ormond Street Hospital Biomedical Research Centre, 5Genetics and Genomic Medicine Research and Teaching Department, Great Ormond Street Institute of Child Health,University College London
Summary
Nous détaillons ici un protocole optimisé pour l’injection latérale de la veine caudale chez la souris afin d’administrer systématiquement le virus adéno-associé (AAV) chez les souris adultes. De plus, nous décrivons les protocoles des tests couramment utilisés pour évaluer la transduction des AAV.
