Simon J. Boulton Artios Pharma Ltd, Cambridge Biography Publications Institution JoVE Articles Simon J. Boulton has not added a biography. If you are Simon J. Boulton and would like to personalize this page please email our Author Liaison for assistance. Publications Micronuclei Induced by Radiation, Replication Stress, or Chromosome Segregation Errors Do Not Activate CGAS-STING Molecular Cell. Jun, 2024 | Pubmed ID: 38749421 Extraordinary Collateral Mutagenesis Induced by CX-5461 Nature Genetics. Jan, 2024 | Pubmed ID: 38129540 Visualization of Direct and Diffusion-assisted RAD51 Nucleation by Full-length Human BRCA2 Protein Molecular Cell. Aug, 2023 | Pubmed ID: 37499663 POLQ Seals Post-replicative SsDNA Gaps to Maintain Genome Stability in BRCA-deficient Cancer Cells Molecular Cell. Dec, 2022 | Pubmed ID: 36455556 H3K4 Methylation by SETD1A/BOD1L Facilitates RIF1-dependent NHEJ Molecular Cell. May, 2022 | Pubmed ID: 35439434 HELQ is a Dual-function DSB Repair Enzyme Modulated by RPA and RAD51 Nature. Jan, 2022 | Pubmed ID: 34937945 Tackling PARP Inhibitor Resistance Trends in Cancer. Dec, 2021 | Pubmed ID: 34563478 Mechanism of Mitotic Recombination: Insights from C. Elegans Current Opinion in Genetics & Development. Dec, 2021 | Pubmed ID: 34186335 Oncogenic Herpesvirus KSHV Triggers Hallmarks of Alternative Lengthening of Telomeres Nature Communications. Jan, 2021 | Pubmed ID: 33479235 Single-molecule Analysis Reveals Cooperative Stimulation of Rad51 Filament Nucleation and Growth by Mediator Proteins Molecular Cell. Mar, 2021 | Pubmed ID: 33421363 Defective ALC1 Nucleosome Remodeling Confers PARPi Sensitization and Synthetic Lethality with HRD Molecular Cell. Feb, 2021 | Pubmed ID: 33333017 TRF2-independent Chromosome End Protection During Pluripotency Nature. Jan, 2021 | Pubmed ID: 33239783 Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases Trends in Genetics : TIG. Apr, 2021 | Pubmed ID: 33041047 RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions Cell Reports. Dec, 2020 | Pubmed ID: 33357438 Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch Cell Reports. Dec, 2020 | Pubmed ID: 33357431 Synthetic Lethality Between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication Cell Reports. May, 2020 | Pubmed ID: 32460026 CDK Phosphorylation of TRF2 Controls T-loop Dynamics During the Cell Cycle Nature. Nov, 2019 | Pubmed ID: 31723267 SLX4IP Antagonizes Promiscuous BLM Activity During ALT Maintenance Molecular Cell. 10, 2019 | Pubmed ID: 31447390 IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer Molecular Cell. Aug, 2019 | Pubmed ID: 31302002 A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs Cell Reports. Jan, 2019 | Pubmed ID: 30650366 Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-based Reporter Assays Diego Grande*1, Eeson Rajendra*1, Bethany Mason1, Alessandro Galbiati1, Simon J. Boulton1,2, Graeme C. M. Smith1, Helen M. R. Robinson1 1Artios Pharma Ltd, Cambridge, 2The Francis Crick Institute, London JoVE 66969 Pesquisa do câncer
Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-based Reporter Assays Diego Grande*1, Eeson Rajendra*1, Bethany Mason1, Alessandro Galbiati1, Simon J. Boulton1,2, Graeme C. M. Smith1, Helen M. R. Robinson1 1Artios Pharma Ltd, Cambridge, 2The Francis Crick Institute, London JoVE 66969 Pesquisa do câncer
