Nicolas Schlegel Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, Department of Surgery I University of Würzburg Biography Publications Institution JoVE Articles Nicolas Schlegel has not added a biography. If you are Nicolas Schlegel and would like to personalize this page please email our Author Liaison for assistance. Publications G6b-B Regulates an Essential Step in Megakaryocyte Maturation Blood Advances. Feb, 2022 | Pubmed ID: 35134123 Clinical Presentation, Treatment, and Outcome of Parathyroid Carcinoma: Results of the NEKAR Retrospective International Multicenter Study Annals of Surgery. 02, 2022 | Pubmed ID: 32649472 Evaluation of Diagnostic Efficacy for Localization of Parathyroid Adenoma in Patients with Primary Hyperparathyroidism Undergoing Repeat Surgery Langenbeck's Archives of Surgery. Aug, 2021 | Pubmed ID: 33993327 Prognostic Impact of Additive Chemotherapy After Curative Resection of Metachronous Colorectal Liver Metastasis: a Single-centre Retrospective Study BMC Cancer. May, 2021 | Pubmed ID: 33941104 Case Report: Abdominal Lymph Node Metastases of Parathyroid Carcinoma: Diagnostic Workup, Molecular Diagnosis, and Clinical Management Frontiers in Endocrinology. 2021 | Pubmed ID: 33833736 Serum-derived Factors of Breast Cancer Patients with Brain Metastases Alter Permeability of a Human Blood-brain Barrier Model Fluids and Barriers of the CNS. Apr, 2020 | Pubmed ID: 32321535 Mortality and Complications Following Visceral Surgery: A Nationwide Analysis Based on the Diagnostic Categories Used in German Hospital Invoicing Data Deutsches Arzteblatt International. 11, 2019 | Pubmed ID: 31774053 Prognostic Relevance of Steroid Sulfation in Adrenocortical Carcinoma Revealed by Molecular Phenotyping Using High-Resolution Mass Spectrometry Imaging Clinical Chemistry. 10, 2019 | Pubmed ID: 31492715 Correction To: Dsg2 Via Src-mediated Transactivation Shapes EGFR Signaling Towards cell Adhesion Cellular and Molecular Life Sciences : CMLS. 09, 2019 | Pubmed ID: 31292664 Ureaplasma Species Modulate Cell Adhesion Molecules and Growth Factors in Human Brain Microvascular Endothelial Cells Cytokine. 09, 2019 | Pubmed ID: 31158700 Desmoglein 2, but Not Desmocollin 2, Protects Intestinal Epithelia from Injury Mucosal Immunology. 11, 2018 | Pubmed ID: 30115995 Dsg2 Via Src-mediated Transactivation Shapes EGFR Signaling Towards Cell Adhesion Cellular and Molecular Life Sciences : CMLS. Nov, 2018 | Pubmed ID: 29980799 Sphingosine-1-Phosphate Receptor-1 Agonist Sew2871 Causes Severe Cardiac Side Effects and Does Not Improve Microvascular Barrier Breakdown in Sepsis Shock (Augusta, Ga.). Jan, 2018 | Pubmed ID: 28538086 [Expectations of Visceral Surgeons from the Results of Clinical Autopsies] Der Pathologe. Sep, 2017 | Pubmed ID: 28660345 [Updated Definition of Sepsis : Implications for Diagnostics and Therapy Principles] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jan, 2017 | Pubmed ID: 27975124 The Glial Cell-line Derived Neurotrophic Factor: a Novel Regulator of Intestinal Barrier Function in Health and Disease American Journal of Physiology. Gastrointestinal and Liver Physiology. 06, 2016 | Pubmed ID: 27151942 Balanced Hydroxyethylstarch (HES 130/0.4) Impairs Kidney Function In-Vivo Without Inflammation PloS One. 2015 | Pubmed ID: 26340751 Glial Cell Line-derived Neurotrophic Factor Promotes Barrier Maturation and Wound Healing in Intestinal Epithelial Cells in Vitro American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2015 | Pubmed ID: 26294673 Soluble VE-cadherin is Involved in Endothelial Barrier Breakdown in Systemic Inflammation and Sepsis Cardiovascular Research. Jul, 2015 | Pubmed ID: 25975259 Sphincter-sparing Intersphincteric Rectal Resection As an Alternative to Proctectomy in Long-standing Fistulizing and Stenotic Crohn's Proctitis? International Journal of Colorectal Disease. May, 2015 | Pubmed ID: 25847822 Phosphodiesterase-4 Inhibition with Rolipram Attenuates Hepatocellular Injury in Hyperinflammation in Vivo and in Vitro Without Influencing Inflammation and HO-1 Expression Journal of Pharmacology & Pharmacotherapeutics. Jan-Mar, 2015 | Pubmed ID: 25709347 Sepsis-induced Acute Kidney Injury by Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Reproducible Animal Model Intensive Care Medicine Experimental. Dec, 2014 | Pubmed ID: 26266931 E7080 (lenvatinib), a Multi-targeted Tyrosine Kinase Inhibitor, Demonstrates Antitumor Activities Against Colorectal Cancer Xenografts Neoplasia (New York, N.Y.). Nov, 2014 | Pubmed ID: 25425971 [Is a Different View on the Pathophysiology of Sepsis the Key for Novel Therapeutic Options?] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Aug, 2014 | Pubmed ID: 25103839 Phosphodiesterase 4 Inhibition Dose Dependently Stabilizes Microvascular Barrier Functions and Microcirculation in a Rodent Model of Polymicrobial Sepsis Shock (Augusta, Ga.). Jun, 2014 | Pubmed ID: 24569506 Effects of Crystalloids and Colloids on Liver and Intestine Microcirculation and Function in Cecal Ligation and Puncture Induced Septic Rodents BMC Gastroenterology. Dec, 2012 | Pubmed ID: 23245375 Role of NF-κB Activation in LPS-induced Endothelial Barrier Breakdown Histochemistry and Cell Biology. Oct, 2012 | Pubmed ID: 22718247 Phosphodiesterase-4 Inhibition As a Therapeutic Approach to Treat Capillary Leakage in Systemic Inflammation The Journal of Physiology. Jun, 2012 | Pubmed ID: 22495586 Atrial Natriuretic Peptide Enhances Microvascular Albumin Permeability by the Caveolae-mediated Transcellular Pathway Cardiovascular Research. Jan, 2012 | Pubmed ID: 22025581 Pulmonary Effects of Positive End-expiratory Pressure and Fluid Therapy in Experimental Lung Injury Experimental Lung Research. Feb, 2011 | Pubmed ID: 21077780 Differential Role of Rho GTPases in Intestinal Epithelial Barrier Regulation in Vitro Journal of Cellular Physiology. May, 2011 | Pubmed ID: 20945370 Desmoglein 2-mediated Adhesion is Required for Intestinal Epithelial Barrier Integrity American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2010 | Pubmed ID: 20224006 The Impact of Crystalloid and Colloid Infusion on the Kidney in Rodent Sepsis Intensive Care Medicine. Mar, 2010 | Pubmed ID: 19890625 Impaired CAMP and Rac 1 Signaling Contribute to TNF-alpha-induced Endothelial Barrier Breakdown in Microvascular Endothelium Microcirculation (New York, N.Y. : 1994). Aug, 2009 | Pubmed ID: 19504398 Endothelial Barrier Stabilization by a Cyclic Tandem Peptide Targeting VE-cadherin Transinteraction in Vitro and in Vivo Journal of Cell Science. May, 2009 | Pubmed ID: 19420236 Impaired Integrin-mediated Adhesion Contributes to Reduced Barrier Properties in VASP-deficient Microvascular Endothelium Journal of Cellular Physiology. Aug, 2009 | Pubmed ID: 19347869 Lipopolysaccharide-induced Endothelial Barrier Breakdown is Cyclic Adenosine Monophosphate Dependent in Vivo and in Vitro Critical Care Medicine. May, 2009 | Pubmed ID: 19325485 Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury Natalie Burkard1, Wolfgang Baar2,3, Sven Flemming1, Nicolas Schlegel1, Jakob Wollborn2,3, Reinhard Schneider4, Robert W Brock5, Christian Wunder6, Martin Alexander Schick2,3 1Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, Department of Surgery I, University of Würzburg, 2Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, 3Faculty of Medicine, University of Freiburg, 4Department of Internal Medicine I, Division of Nephrology, University of Würzburg, 5Department of Physiology and Pharmacology, West Virginia University School of Medicine, Robert C. Byrd Health Science Center, 6Department of Anesthesiology and Intensive Care Medicine, Robert-Bosch-Krankenhaus JoVE 54448 Imunologia e Infecção
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury Natalie Burkard1, Wolfgang Baar2,3, Sven Flemming1, Nicolas Schlegel1, Jakob Wollborn2,3, Reinhard Schneider4, Robert W Brock5, Christian Wunder6, Martin Alexander Schick2,3 1Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, Department of Surgery I, University of Würzburg, 2Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, 3Faculty of Medicine, University of Freiburg, 4Department of Internal Medicine I, Division of Nephrology, University of Würzburg, 5Department of Physiology and Pharmacology, West Virginia University School of Medicine, Robert C. Byrd Health Science Center, 6Department of Anesthesiology and Intensive Care Medicine, Robert-Bosch-Krankenhaus JoVE 54448 Imunologia e Infecção