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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

17,886 Views

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09:25 min

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May 31, 2016

DOI:

10.3791/54052-v

DOI:
10.3791/54052-v

•

09:25 min
May 31, 2016

•

14 Views
, ,
1Laboratory of Endocrinology and Receptor Biology,National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 2Murine Phenotyping Core,National Heart, Lung, and Blood Institute, National Institutes of Health

Summary

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Fatigue is a common, undertreated and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding and future treatment of fatigue. To that end, the current protocol provides a novel means of measuring fatigue-like behavior in the mouse.

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Dougherty, J. P., Springer, D. A., Gershengorn, M. C. The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse. J. Vis. Exp. (111), e54052, doi:10.3791/54052 (2016).

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