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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

10,306 Views

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08:42 min

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May 19, 2015

DOI:

10.3791/52061-v

DOI:
10.3791/52061-v

•

08:42 min
May 19, 2015

•

8 Views
, , , ,
1Department of Psychiatry and Behavioural Neurosciences,McMaster University, 2McMaster Integrative Neuroscience Discovery and Study,McMaster University, 3Department of Psychiatry,University of Calgary, 4Department of Psychology, Neuroscience & Behaviour,McMaster University

Summary

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We aim to identify the neural correlates underlying sustained and transient thought suppression, and thought re-emergence in controls, at-risk and depressed individuals. Activation was greatest for controls compared to the at-risk and the depressed group in the dorsolateral prefrontal cortex during thought suppression and anterior cingulate cortex during thought re-emergence.

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FMRIThought SuppressionDepressionRuminationDorsolateral Prefrontal CortexAnterior Cingulate CortexAt-riskMajor Depressive Disorder

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Cite this Article

Carew, C. L., Tatham, E. L., Milne, A. M., MacQueen, G. M., Hall, G. B. Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression. J. Vis. Exp. (99), e52061, doi:10.3791/52061 (2015).

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