Journal
/
Biochemistry
/
Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
/
Author Spotlight: Developing Acetyl-Click Assay for HAT1 Inhibitor Screening
JoVE Journal
Biochemistry
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Biochemistry
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation

Author Spotlight: Developing Acetyl-Click Assay for HAT1 Inhibitor Screening

English

Automatically Generated

457 Views

•

01:28 min

•

January 26, 2024

DOI:

10.3791/66054-v

DOI:
10.3791/66054-v

•

01:28 min
January 26, 2024

•

13 Views
, , ,
1Departments of Internal Medicine and the Green Center for Reproductive Biology Sciences,University of Texas Southwestern Medical Center, 2Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences,Wayne State University

Explore More Videos

Acetyl-Click Chemistry AssayHistone Acetyltransferase 1 (HAT1)Acetyl Transferase ActivityHigh Throughput ScreeningSmall Molecule InhibitorsPeptide SubstrateEnzymatic AssayChromatin SynthesisTumor GrowthCancer Treatment

Read Article

Cite this Article

Rajkumar, S., Dixon, D., Lipchik, A. M., Gruber, J. J. An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation. J. Vis. Exp. (203), e66054, doi:10.3791/66054 (2024).

Download .ris file

Copy

Share Video

.

Copy