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February 17, 2023
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The streptozotocin-induced diabetic wound model in male SD rats is currently the most widely used model for studying wound healing in type I diabetes mellitus. This protocol describes the methods used to construct this model. It also presents and addresses potential challenges and examines the progression and angiogenic characteristics of diabetic wounds.
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Wang, W., Bai, D., Wu, C., Li, H., Xie, X., Ji, W., Gao, J. A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes. J. Vis. Exp. (192), e64914, doi:10.3791/64914 (2023).
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