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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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JoVE Journal Chemistry
Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

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2,326 Views

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08:56 min

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November 30, 2022

DOI:

10.3791/64571-v

DOI:
10.3791/64571-v

•

08:56 min
November 30, 2022

•

7 Views
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1C. Eugene Bennett Department of Chemistry,West Virginia University

Summary

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The present protocol describes a detailed benchtop catalytic method that yields a unique borylated derivative of ibuprofen. 

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Knowlden, S. W., Abeysinghe, R. T., Swistok, A. D., Ravenscroft, A. C., Popp, B. V. Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions. J. Vis. Exp. (189), e64571, doi:10.3791/64571 (2022).

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