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Burn Injury-Induced Pain and Depression-Like Behavior in Mice
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Neuroscience
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JoVE Journal Neuroscience
Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

English

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2,851 Views

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07:08 min

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September 29, 2021

DOI:

10.3791/62817-v

DOI:
10.3791/62817-v

•

07:08 min
September 29, 2021

•

4 Views
, , , , , ,
1Department of Physiology and Medical Science, College of Medicine and Brain Research Institute,Chungnam National University, 2Department of Pharmacology,Catholic Kwandong University College of Medicine

Summary

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A transient scald injury (65 °C ± 0.5 °C, 3 s) of one hind paw decreases the threshold (g) to von Frey filament stimulation of the ipsilateral side and alters gait pattern. Besides, burn injury induces depression-like behavior in the forced swimming test.

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Cite this Article

Choi, J., Kang, D., Kim, J., Lee, M., Choi, S., Park, J. B., Kim, H. Burn Injury-Induced Pain and Depression-Like Behavior in Mice. J. Vis. Exp. (175), e62817, doi:10.3791/62817 (2021).

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