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GM-Free Generation of Blood-Derived Neuronal Cells
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
GM-Free Generation of Blood-Derived Neuronal Cells

GM-Free Generation of Blood-Derived Neuronal Cells

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08:11 min

February 13, 2021

DOI:

08:11 min
February 13, 2021

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Summary

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We present a genetically modified-free (GM-free) method to obtain cells with a neuronal phenotype from reprogrammed peripheral blood cells. Activation of a signaling pathway linked to novel human GPI-linked protein reveals an efficient GM-free method for obtaining human pluripotent stem cells.

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