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A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
JoVE Journal
Genetics
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JoVE Journal Genetics
A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

English

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2,956 Views

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05:01 min

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July 01, 2020

DOI:

10.3791/61268-v

DOI:
10.3791/61268-v

•

05:01 min
July 01, 2020

•

2 Views
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1Institute for Genomics, Biocomputing & Biotechnology,Mississippi State University, 2Corn Host Plant Resistance Research Unit,USDA-ARS

Summary

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By running the Pathway Association Study Tool (PAST), either through the Shiny application or through the R console, researchers can gain a deeper understanding of the biological meaning of their genome-wide association study (GWAS) results by investigating the metabolic pathways involved.

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GWASGenome-wide Association AnalysisMetabolic PathwayPASTPathway Association Study ToolSNPsLinkage DisequilibriumGene AnnotationPathway AnalysisRug PlotsR ConsoleShiny

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Cite this Article

Thrash, A., Warburton, M. L. A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information. J. Vis. Exp. (161), e61268, doi:10.3791/61268 (2020).

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