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Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal Bioengineering
Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator

Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator

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07:06 min

May 14, 2020

DOI:

07:06 min
May 14, 2020

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Summary

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Presented here is a protocol for the primary clarification of CHO cell culture using an acoustic separator. This protocol can be used for the primary clarification of shake flask cultures or bioreactor harvests and has the potential application for continuous clarification of the cell bleed material during perfusion bioreactor operations.

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