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Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
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Neuroscience
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JoVE Journal Neuroscience
Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia

Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia

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9,988 Views

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14:53 min

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June 26, 2020

DOI:

10.3791/61119-v

DOI:
10.3791/61119-v

•

14:53 min
June 26, 2020

•

4 Views
, , ,
1College of Public Health,Shaanxi University of Chinese Medicine, 2Spinal Cord and Brain Injury Research Center, Department of Physiology,University of Kentucky

Summary

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A method for delivering neural stem cells, adaptable for injecting solutions or suspensions, through the common carotid artery (mouse) or external carotid artery (rat) after ischemic stroke is reported. Injected cells are distributed broadly throughout the brain parenchyma and can be detected up to 30 d after delivery.

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Cite this Article

Zhang, B., Joseph, B., Saatman, K. E., Chen, L. Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia. J. Vis. Exp. (160), e61119, doi:10.3791/61119 (2020).

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