Presented here is a protocol to assess biventricular heart function in mice by generating pressure-volume (PV) loops from the right and left ventricle in the same animal using closed chest catheterization. The focus is on the technical aspect of surgery and data acquisition.
Potus, F., Martin, A. Y., Snetsinger, B., Archer, S. L. Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice. J. Vis. Exp. (160), e61088, doi:10.3791/61088 (2020).