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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

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8,741 Views

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00:07 min

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August 30, 2019

DOI:

10.3791/60024-v

DOI:
10.3791/60024-v

•

00:07 min
August 30, 2019

•

4 Views
, , ,
1Pulmonary and Critical Care Medicine, Department of Internal Medicine,Brigham and Women’s Hospital, Harvard Medical School

Summary

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Selective intra-bronchial acid instillation to the left lung in mice results in unilateral and self-limited acute lung injury that models human acute respiratory distress syndrome (ARDS) induced by gastric acid aspiration.

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Cite this Article

Tavares, A. H., Colby, J. K., Levy, B. D., Abdulnour, R. E. A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation. J. Vis. Exp. (150), e60024, doi:10.3791/60024 (2019).

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