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Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

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8,693 Views

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08:30 min

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January 19, 2019

DOI:

10.3791/58771-v

DOI:
10.3791/58771-v

•

08:30 min
January 19, 2019

•

5 Views
,
1Molecular Diagnostics, Centre for Health and Bioresources,AIT Austrian Institute of Technology GmbH

Summary

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Here, a protocol for the protection of DNA origami nanostructures in Mg-depleted and nuclease-rich media using natural cationic polysaccharide chitosan and synthetic linear polyethyleneimine (LPEI) coatings is presented.

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Cite this Article

Ahmadi, Y., Barisic, I. Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures. J. Vis. Exp. (143), e58771, doi:10.3791/58771 (2019).

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