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Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

JoVE Journal
Genetics

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JoVE Journal Genetics

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

9,289 Views

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09:30 min

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September 13, 2018

DOI:

10.3791/57731-v

DOI:

10.3791/57731-v

•

09:30 min

September 13, 2018

•

2 Views

Clark Fritsch^1,2, Jean-Francois Pierre Gout^3,4, Marc Vermulst¹

¹Center for Mitochondrial and Epigenomic Medicine,Children’s Hospital of Philadelphia, ²Department of Cellular and Molecular Biology,University of Pennsylvania, ³Department of Biological Sciences,Mississippi State University, ⁴Center for Mechanisms of Evolution, Biodesign Institute,Arizona State University

Summary

This protocol provides researchers with a new tool to monitor the fidelity of transcription in multiple model organisms.

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