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07:54 min
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June 29, 2018
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Rats' anxiety-like behavior tested by the elevated plus maze varies highly depending on the testing environment. Here we show how apparatus settings, especially arm structure, affect behavior on the maze, and we explain a reliable protocol to detect effects of anxiolytic drugs. This report will contribute to anxiety research.
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Horii, Y., McTaggart, I., Kawaguchi, M. Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test. J. Vis. Exp. (136), e56428, doi:10.3791/56428 (2018).
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