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An Inexpensive, Scalable Behavioral Assay for Measuring Ethanol Sedation Sensitivity and Rapid Tolerance in Drosophila
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Neuroscience
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JoVE Journal Neuroscience
An Inexpensive, Scalable Behavioral Assay for Measuring Ethanol Sedation Sensitivity and Rapid Tolerance in Drosophila

An Inexpensive, Scalable Behavioral Assay for Measuring Ethanol Sedation Sensitivity and Rapid Tolerance in Drosophila

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10,122 Views

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07:28 min

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April 15, 2015

DOI:

10.3791/52676-v

DOI:
10.3791/52676-v

•

07:28 min
April 15, 2015

•

1 Views
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1Department of Human and Molecular Genetics,Virginia Commonwealth University, 2VCU Alcohol Research Center,Virginia Commonwealth University

Summary

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Straightforward assays for measuring ethanol sensitivity and rapid tolerance in Drosophila facilitate the use of this model organism for investigating these important ethanol-related behaviors. Here, a relatively simple, scalable assay for measuring ethanol sensitivity and rapid tolerance in flies is described.

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Sandhu, S., Kollah, A. P., Lewellyn, L., Chan, R. F., Grotewiel, M. An Inexpensive, Scalable Behavioral Assay for Measuring Ethanol Sedation Sensitivity and Rapid Tolerance in Drosophila. J. Vis. Exp. (98), e52676, doi:10.3791/52676 (2015).

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